Pearl Second Opinion
by Pearl · hellopearl.com ↗
Pearl Second Opinion is an FDA-cleared AI solution for real-time pathology detection on 2D dental X-rays and CBCT scans, integrating with various dental syst...
Data Index profile
Table view
| Axis | Pearl Second Opinion | Basis |
|---|---|---|
| Features | 8.5 | 11 of 13 tracked capabilities confirmed (0 unverified) |
| Integrations | 7.6 | 9 verified integrations |
| Pricing clarity | 2.0 | quote only |
| Support | 4.0 | 2 channels |
| Vendor stability | 8.0 | 501-1000 staff |
| User rating | 8.8 | 4.4/5 from 13 public reviews |
Of the 6 axes we could measure, Pearl Second Opinion is strongest on user rating (8.8/10) and weakest on pricing clarity (2.0/10). It ranks #1 of 14 in AI radiograph analysis, 2.5 points above the category median of 4.4.
- Features8.5
11 of 13 tracked capabilities confirmed (0 unverified). What this measures ⓘ
- Integrations7.6
9 verified integrations. What this measures ⓘ
- Pricing clarity2.0
quote only. What this measures ⓘ
- Support4.0
2 channels. What this measures ⓘ
- Vendor stability8.0
501-1000 staff. What this measures ⓘ
- User rating8.8
4.4/5 from 13 public reviews. What this measures ⓘ
AI transparency
1 of 3 AI transparency signals disclosed. Across all AI tools we track, most vendors disclose none of them — which is why we show this panel on every AI product.
Compliance & security
| Market | Status | Number | Date | Source |
|---|---|---|---|---|
| United States | FDA 510(k) cleared | K242522 ↗ | — | press release ↗ |
| United States | FDA 510(k) cleared | K242600 ↗ | — | press release ↗ |
| United States | FDA 510(k) cleared | K243234 ↗ | — | press release ↗ |
“Claimed by vendor” means a public statement we could cite; it is not an audit. Ask for the SOC 2 report or signed BAA before you share patient data.
AI imaging coverage
Pearl Second Opinion confirms 11 of 13 capabilities we track for this category. Relatively rare among its 13 peers: calculus, chairside patient view, and claim support.
- ✓ Bitewing
- ✓ Periapical
- ✓ Panoramic
- ✓ CBCT
- ✕ Intraoral photo
- ✓ Caries
- ✓ Calculus
- ✓ Bone loss
- ✓ Periapical lesion
- ✓ Restorations
- ✕ Segmentation
- ✓ Chairside patient view
- ✓ Claim support
- Imaging integrations
- DEXIS IS 3800, Planmeca Romexis, Sidexis 4, SOTA Cloud, tab32, Open Dental, Eaglesoft, Curve Dental, Dentally
See how every AI radiograph analysis product compares on these features →
Integration web
Pearl Second Opinion lists 9 verified integrations, all native. It covers 3 of the 6 most-connected systems in our database (Open Dental, Eaglesoft, and Curve Dental).
Pricing & 3-year cost
- License model
- Quote only
- Price transparency
- Quote only
- Starting price
- Not published
- Free trial
- Not verified
- Price last checked
- Sep 30, 2026
- Minimum term
- Not verified
- Auto-renew
- Not verified
- Cancellation notice
- Not verified
- Early termination fee
- Not verified
- Data export on exit
- Not verified
Pearl Second Opinion is quote-only — like 8 of 13 other products in this category. 5 competitors publish at least partial pricing.
User ratings
4.4/5 averaged across Capterra from 13 reviews. 1 rated competitor in the category scores higher.
Ratings are snapshots from third-party platforms, shown with their date and link. We do not publish them as our own review stars.
Who it’s for
Practice size
- Specialties
- General, Pediatric, Orthodontics, Oral surgery, Periodontics, Endodontics, Prosthodontics, Cosmetic
- Deployment
- Cloud
- Open API
- ?
- Support
- phone, email
Company
- Vendor
- Pearl
- Employees
- 501-1000
- Customers (vendor claim)
- 10,000
Markets
Vendor also markets the product globally.
Markets the vendor actively sells into: Global.
FAQ
How much does Pearl Second Opinion cost?
Pearl Second Opinion does not publish pricing; it is sold on a quote basis. 4 competitors in AI radiograph analysis publish a starting price.
Is Pearl Second Opinion HIPAA compliant?
Yes — Pearl Second Opinion's vendor states HIPAA compliance. Always request a signed BAA before sharing PHI.
What does Pearl Second Opinion integrate with?
We verified 9 integrations: DEXIS IS 3800, Planmeca Romexis, Sidexis 4, SOTA Cloud, tab32, Open Dental, Eaglesoft, and Curve Dental and others.
What are the best alternatives to Pearl Second Opinion?
By our Data Index, the strongest alternatives in AI radiograph analysis are Denti.AI (5.9), Overjet (5.4), and CranioCatch (5.2).
Where is the Pearl Second Opinion login?
Pearl Second Opinion accounts are accessed through the vendor's official site, hellopearl.com. Denture-ID is an independent review site and cannot access or reset Pearl Second Opinion accounts — use the vendor's own login and password-reset pages.
Is Pearl Second Opinion FDA cleared?
Yes. We found 3 FDA records: FDA 510(k) cleared (K242522); FDA 510(k) cleared (K242600); FDA 510(k) cleared (K243234). Clearances apply to specific indications, so check that the finding you rely on is covered.
Sources12 cited · 23 field-level citations
- Second Opinion® AI for Dental X-Rays | Pearl · hellopearl.com · vendor site
- Pearl AI - Help Center · help.hellopearl.com · vendor docs
- Second Opinion 3D™ AI for Dental CBCT Scans | Pearl · hellopearl.com · vendor site
- Request a Demo – Pearl · hellopearl.com · vendor site
- Pearl Expands FDA-Cleared Second Opinion® with Precision Segmentation Capabilities · hellopearl.com · press release
- Pearl Partners with Open Dental to Offer AI-Powered Diagnostic Imaging - Pearl · hellopearl.com · press release
- Pearl: Dental AI & Practice Intelligence for Dental Practices & DSOs · hellopearl.com · vendor site
- Dental AI for DSOs and Large Group Practices - Pearl · hellopearl.com · vendor site
- Dental AI for Dentists - Pearl · hellopearl.com · vendor site
- Pearl | LinkedIn · linkedin.com · vendor site
- Pearl Becomes First Dental AI Company Cleared by FDA for Both 2D and 3D Imaging - Pearl · hellopearl.com · press release
- Navigating Dental Insurance Friction with AI - Pearl · hellopearl.com · vendor site
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