Closed systems (one vendor from scan to mill) are simpler to support; open systems let you pick best-of-breed components and change one without replacing everything. Subscription requirements are a newer form of lock-in to check.
Where lock-in appears
Proprietary scan formats, mandatory cloud subscriptions, export fees, resins or milling blocks coded to one machine and practice management systems without an API.
The case for each
Closed systems offer one vendor to call, validated workflows and less set-up. Open systems let you replace one component at a time and shop for materials and lab services. Many vendors now sit in between, offering an open mode alongside validated workflows.